Projects

research work
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Computational VHH Binder Design for Tumor-Specific Splice Variants

A computational pipeline for designing nanobody binders against spliced neo-antigen proteins expressed on cancer cells but not healthy tissue, built on AlphaFold2-guided gradient descent.
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CAR T Cell Therapy Targeting IGHV4-34 B Cell Malignancies

Contributed to the development of CART4-34, a precision CAR T cell therapy targeting IGHV4-34+ B cell malignancies, published in Science Translational Medicine (2026). My work focused on solving a transduction efficiency bottleneck in CAR T cell manufacturing.
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Reference-free Cell Type Annotation with LLM Agents

An LLM agent framework for automated, reference-free cell type annotation in high-resolution spatial transcriptomics data. Published at ICLR 2025 Workshop on Machine Learning for Genomics Explorations (MLGenX).
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Biosecurity Policy Enforcement for AI Protein Design Agents

A policy-as-code biosecurity guardrail for AI-driven DNA synthesis agents, built with Cedar policies and the Sondera Harness SDK. Won first place at the Sondera AI hackathon.

class projects
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Multi-modal Sequence Encoding for AMPs

Benchmarking peptide sequence encoders and multi-modal transfer learning for out-of-distribution generalization. CIS 5200 (Machine Learning).
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Music Genre Classification

Classification model to predict the genre of a Spotify song based on its audio features. Final project for CIS 5450 (Big Data Analytics).
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Simplified Phase Vocoder

Implementation of a simplified phase vocoder system in MATLAB to tune vocal input to the C Major scale. BE 3010 (Signals & Systems).
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Cell Movement and Morphology Analysis

Tracking cells over using CV and microscopy images. ENGR 1050 (Scientific Computing).